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1

Shape effects of filaments versus spherical particles in flow and drug delivery

Geng, Yan, Dalhaimer, Paul, Cai, Shenshen, Tsai, Richard, Tewari, Manorama, Minko, Tamara, Discher, Dennis E.

Journal:

Nature Nanotechnology

Year:

2007

Language:

english

File:

PDF, 575 KB

english, 2007

2

Matrix Elasticity Directs Stem Cell Lineage Specification

Adam J. Engler, Shamik Sen, H. Lee Sweeney, Dennis E. Discher

Journal:

Year:

2006

Language:

english

File:

PDF, 940 KB

english, 2006

3

Polymer vesicles in vivo: correlations with PEG molecular weight

Peter J. Photos, Lucie Bacakova, Bohdana Discher, Frank S. Bates, Dennis E. Discher

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 530 KB

english, 2003

4

POLYMERSOMES

Discher, Dennis E., Ahmed, Fariyal

Journal:

Annual Review of Biomedical Engineering

Year:

2006

Language:

english

File:

PDF, 606 KB

english, 2006

5

Indentation and Adhesive Probing of a Cell Membrane with AFM: Theoretical Model and Experiments

Sen, Shamik, Subramanian, Shyamsundar, Discher, Dennis E.

Journal:

Biophysical Journal

Year:

2005

Language:

english

File:

PDF, 423 KB

english, 2005

6

From Membranes to Melts, Rouse to Reptation: Diffusion in Polymersome versus Lipid Bilayers

Lee, James C.-M., Santore, Maria, Bates, Frank S., Discher, Dennis E.

Journal:

Year:

2002

Language:

english

File:

PDF, 158 KB

english, 2002

7

From Stealthy Polymersomes and Filomicelles to “Self” Peptide-Nanoparticles for Cancer Therapy

Oltra, Núria Sancho, Nair, Praful, Discher, Dennis E.

Journal:

Annual Review of Chemical and Biomolecular Engineering

Year:

2014

Language:

english

File:

PDF, 3.03 MB

english, 2014

8

Dissipative Particle Dynamics Simulations of Polymersomes

Ortiz, Vanessa, Nielsen, Steven O., Discher, Dennis E., Klein, Michael L., Lipowsky, Reinhard, Shillcock, Julian

Journal:

Journal of Physical Chemistry B

Year:

2005

Language:

english

File:

PDF, 507 KB

english, 2005

9

Block Copolymer Assemblies with Cross-Link Stabilization: From Single-Component Monolayers to Bilayer Blends with PEO−PLA †

Ahmed, Fariyal, Hategan, Alina, Discher, Dennis E., Discher, Bohdana M.

Journal:

Year:

2003

Language:

english

File:

PDF, 375 KB

english, 2003

10

Networks with fourfold connectivity in two dimensions

Tessier, Frédéric, Boal, David H., Discher, Dennis E.

Journal:

Physical Review E

Year:

2003

Language:

english

File:

PDF, 510 KB

english, 2003

11

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor

Dingal, P. C. Dave P., Bradshaw, Andrew M., Cho, Sangkyun, Raab, Matthew, Buxboim, Amnon, Swift, Joe, Discher, Dennis E.

Journal:

Nature Materials

Year:

2015

Language:

english

File:

PDF, 5.87 MB

english, 2015

12

New insights into erythrocyte membrane organization and microelasticity

Discher, Dennis E

Journal:

Current Opinion in Hematology

Year:

2000

Language:

english

File:

PDF, 1006 KB

english, 2000

13

Fractal Heterogeneity in Minimal Matrix Models of Scars Modulates Stiff-Niche Stem-Cell Responses Via Nuclear Exit of a Mechanorepressor

Dingal, P.C. Dave P., Xia, Yuntao, Discher, Dennis E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

14

SnapShot: Mechanosensing Matrix

Irianto, Jerome, Pfeifer, Charlotte R., Xia, Yuntao, Discher, Dennis E.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.37 MB

english, 2016

15

“Marker of Self” CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors

Sosale, Nisha G, Ivanovska, Irena I, Tsai, Richard K, Swift, Joe, Hsu, Jake W, Alvey, Cory M, Zoltick, Philip W, Discher, Dennis E

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2016

Language:

english

File:

PDF, 2.09 MB

english, 2016

16

Inhibition of a DNA Repair Kinase ATM Leads to Cell Death in 3D Migration Independent of DNA Damage

Xia, Yuntao, Irianto, Jerome, Pfeifer, Charlotte, Greenberg, Roger, Discher, Dennis

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 43 KB

english, 2017

17

Matrix Mechanosensing: From Scaling Concepts in ’Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer

Discher, Dennis E., Smith, Lucas, Cho, Sangkyun, Colasurdo, Mark, García, Andrés J., Safran, Sam

Journal:

Annual Review of Biophysics

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

18

Manipulating the mechanics of extracellular matrix to study effects on the nucleus and its structure

Xia, Yuntao, Cho, Sangkyun, Vashisth, Manasvita, Ivanovska, Irena L., Dingal, P.C. Dave P., Discher, Dennis E.

Journal:

Year:

2018

Language:

english

File:

PDF, 926 KB

english, 2018

19

Macrophages eat more after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα

Hayes, Brandon H., Tsai, Richard K., Dooling, Lawrence J., Kadu, Siddhant, Lee, Justine Y., Pantano, Diego, Rodriguez, Pia L., Subramanian, Shyamsundar, Shin, Jae-Won, Discher, Dennis E.

Journal:

Journal of Cell Science

Year:

2020

Language:

english

File:

PDF, 6.02 MB

english, 2020

20

Macrophage checkpoint blockade: results from initial clinical trials, binding analyses, and CD47-SIRPÎ± structureâfunction

Jalil, AbdelAziz R, Andrechak, Jason C, Discher, Dennis E

Journal:

Antibody Therapeutics

Year:

2020

File:

PDF, 1.12 MB

2020

21

Nanoparticle Shape Improves Delivery: Rational Coarse Grain Molecular Dynamics (rCG-MD) of Taxol in Worm-Like PEG-PCL Micelles

Sharon M. Loverde, Michael L. Klein, Dennis E. Discher

Journal:

Advanced Materials

Year:

2012

Language:

english

File:

PDF, 1.72 MB

english, 2012

22

Grafting Short Peptides onto Polybutadiene-block-poly(ethylene oxide): A Platform for Self-Assembling Hybrid Amphiphiles

Yan Geng, Dennis E. Discher, Justyna Justynska, Helmut Schlaad

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 186 KB

english, 2006

23

Grafting Short Peptides onto Polybutadiene-block-poly(ethylene oxide): A Platform for Self-Assembling Hybrid Amphiphiles

Yan Geng, Dennis E. Discher, Justyna Justynska, Helmut Schlaad

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

24

Preparation, stability, and in vitro performance of vesicles made with diblock copolymers

James C-M. Lee, Harry Bermudez, Bohdana M. Discher, Maureen A. Sheehan, You-Yeon Won, Frank S. Bates, Dennis E. Discher

Journal:

Biotechnology and Bioengineering

Year:

2001

Language:

english

File:

PDF, 968 KB

english, 2001

25

Post-translational regulation of expression and conformation of an immunoglobulin domain in yeast surface display

Ranganath Parthasarathy, Shyamsundar Subramanian, Eric T. Boder, Dennis E. Discher

Journal:

Biotechnology and Bioengineering

Year:

2006

Language:

english

File:

PDF, 348 KB

english, 2006

26

Exon-skipped dystrophins for treatment of Duchenne muscular dystrophy: Mass spectrometry mapping of most exons and cooperative domain designs based on single molecule mechanics

Christine Carag Krieger, Nishant Bhasin, Manorama Tewari, Andre E. X. Brown, Daniel Safer, H. Lee Sweeney, Dennis E. Discher

Journal:

Year:

2010

Language:

english

File:

PDF, 842 KB

english, 2010

27

Polymersomes as viral capsid mimics

Fariyal Ahmed, Peter J. Photos, Dennis E. Discher

Journal:

Drug Development Research

Year:

2006

Language:

english

File:

PDF, 424 KB

english, 2006

28

Lung vascular targeting through inhalation delivery: Insight from filamentous viruses and other shapes

Abdullah Mahmud, Dennis E. Discher

Journal:

Year:

2011

Language:

english

File:

PDF, 225 KB

english, 2011

29

Polymer Vesicles with a Red Cell-like Surface Charge: Microvascular Imaging and in vivo Tracking with Near-Infrared Fluorescence

David A. Christian, Olga B. Garbuzenko, Tamara Minko, Dennis E. Discher

Journal:

Macromolecular Rapid Communications

Year:

2010

Language:

english

File:

PDF, 503 KB

english, 2010

30

Protein unfolding accounts for the unusual mechanical behavior of fibrin networks

Prashant K. Purohit, Rustem I. Litvinov, Andre E.X. Brown, Dennis E. Discher, John W. Weisel

Journal:

Acta Biomaterialia

Year:

2011

Language:

english

File:

PDF, 1006 KB

english, 2011

31

Visualization of degradable worm micelle breakdown in relation to drug release

Yan Geng, Dennis E. Discher

Journal:

Year:

2006

Language:

english

File:

PDF, 337 KB

english, 2006

32

Emerging applications of polymersomes in delivery: From molecular dynamics to shrinkage of tumors

Dennis E. Discher, Vanessa Ortiz, Goundla Srinivas, Michael L. Klein, Younghoon Kim, David Christian, Shenshen Cai, Peter Photos, Fariyal Ahmed

Journal:

Progress in Polymer Science

Year:

2007

Language:

english

File:

PDF, 1.45 MB

english, 2007

33

Surface probe measurements of the elasticity of sectioned tissue, thin gels and polyelectrolyte multilayer films: Correlations between substrate stiffness and cell adhesion

Adam J. Engler, Ludovic Richert, Joyce Y. Wong, Catherine Picart, Dennis E. Discher

Journal:

Surface Science

Year:

2004

Language:

english

File:

PDF, 493 KB

english, 2004

34

Polymer vesicles in various media

Bohdana M. Discher, Daniel A. Hammer, Frank S. Bates, Dennis E. Discher

Journal:

Current Opinion in Colloid & Interface Science

Year:

2000

Language:

english

File:

PDF, 1.47 MB

english, 2000

35

Synthetic cell elements from block copolymers – hydrodynamic aspects

Paul Dalhaimer, Frank S. Bates, Helim Aranda-Espinoza, Dennis Discher

Journal:

Comptes Rendus Physique

Year:

2003

File:

PDF, 348 KB

2003

36

Biopolymer mimicry with polymeric wormlike micelles: Molecular weight scaled flexibility, locked-in curvature, and coexisting microphases

Paul Dalhaimer, Harry Bermudez, Dennis E. Discher

Journal:

Journal of Polymer Science Part B: Polymer Physics

Year:

2004

Language:

english

File:

PDF, 254 KB

english, 2004

37

Computer simulation of aqueous block copolymer assemblies: Length scales and methods

Vanessa Ortiz, Steven O. Nielsen, Michael L. Klein, Dennis E. Discher

Journal:

Journal of Polymer Science Part B: Polymer Physics

Year:

2006

Language:

english

File:

PDF, 202 KB

english, 2006

38

Block copolymer worm micelles in dilution: Mechanochemical metrics of robustness as a basis for novel linear assemblies

Kandaswamy Vijayan, Dennis E. Discher

Journal:

Journal of Polymer Science Part B: Polymer Physics

Year:

2006

Language:

english

File:

PDF, 79 KB

english, 2006

39

Biomechanics: Cell Research and Applications for the Next Decade

Dennis Discher, Cheng Dong, Jeffrey J. Fredberg, Farshid Guilak, Donald Ingber, Paul Janmey, Roger D. Kamm, Geert W. Schmid-Schönbein, Sheldon Weinbaum

Journal:

Annals of Biomedical Engineering

Year:

2009

Language:

english

File:

PDF, 382 KB

english, 2009

40

Micelles of Different Morphologies—Advantages of Worm-like Filomicelles of PEO-PCL in Paclitaxel Delivery

Shenshen Cai, Kandaswamy Vijayan, Debbie Cheng, Eliana M. Lima, Dennis E. Discher

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 573 KB

english, 2007

41

Matrix Strains Induced by Cells: Computing How Far Cells Can Feel

Shamik Sen, Adam J. Engler, Dennis E. Discher

Journal:

Cellular and Molecular Bioengineering

Year:

2009

Language:

english

File:

PDF, 648 KB

english, 2009

42

The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation

Stanley J. Stachelek, Matthew J. Finley, Ivan S. Alferiev, Fengxiang Wang, Richard K. Tsai, Edward C. Eckells, Nancy Tomczyk, Jeanne M. Connolly, Dennis E. Discher, David M. Eckmann, Robert J. Levy

Journal:

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

43

Self-assembly: Towards precision micelles

Discher, Dennis E., Kamien, Randall D.

Journal:

Year:

2004

Language:

english

File:

PDF, 235 KB

english, 2004

44

Developmental biology: Holding it together in the eye

Janmey, Paul A., Discher, Dennis E

Journal:

Year:

2004

Language:

english

File:

PDF, 552 KB

english, 2004

45

Materials science: Embedded shells decalcified

Picart, Catherine, Discher, Dennis E.

Journal:

Year:

2007

Language:

english

File:

PDF, 464 KB

english, 2007

46

Materials science: Bubble wrap of cell-like aggregates

Harada, Takamasa, Discher, Dennis E.

Journal:

Year:

2011

Language:

english

File:

PDF, 713 KB

english, 2011

47

Self-assembly and properties of diblock copolymers by coarse-grain molecular dynamics

Srinivas, Goundla, Discher, Dennis E., Klein, Michael L.

Journal:

Nature Materials

Year:

2004

Language:

english

File:

PDF, 464 KB

english, 2004

48

Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding

Christian, David A., Tian, Aiwei, Ellenbroek, Wouter G., Levental, Ilya, Rajagopal, Karthikan, Janmey, Paul A., Liu, Andrea J., Baumgart, Tobias, Discher, Dennis E.

Journal:

Nature Materials

Year:

2009

Language:

english

File:

PDF, 1.73 MB

english, 2009

49

Stem cells feel the difference

Buxboim, Amnon, Discher, Dennis E

Journal:

Year:

2010

Language:

english

File:

PDF, 628 KB

english, 2010

50

Crosslinked actin networks show liquid crystal elastomer behaviour, including soft-mode elasticity

Dalhaimer, Paul, Discher, Dennis E., Lubensky, Tom C.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.01 MB

english, 2007